Gluten intolerance as a manifestation connective tissue dysplasia (clinical case)

Connective tissue dysplasia (CTD) is manifested by almost all body systems. In the gastrointestinal tract (GIT) with CTD, abnormalities in the structure of the digestive system are mainly detected. Features of the structure and function of enterocytes are rarely described. A clinical case of a 13-year-old adolescent with gluten intolerance suspected of being associated with impaired structure and function of CTDrelated enterocytes is presented. A hypothesis on the possible cause of gluten intolerance due to excessive zonulin formation is proposed, requiring further research.

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