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Progressive fibrosing pulmonary disease: from old misconceptions to a new understanding

https://doi.org/10.24884/1609-2201-2025-104-3-51-58

Abstract

The article presents an analysis of federal clinical guidelines for the diagnosis and treatment of idiopathic pulmonary fibrosis, discusses current problems of diagnosis and treatment of progressive fibrosing pulmonary disease. The authors propose changing the existing medical tactics, this will facilitate early diagnosis and adequate treatment, and therefore improve the prognosis for the life of this category of patients.

About the Authors

M. M. Ilkovich
Pavlov University
Russian Federation

Mikhail M. Ilkovich, Dr. of Sci. (Med.), professor, head of the Department of Pulmonology

Saint Petersburg



L. N. Novikova
Pavlov University
Russian Federation

Lyubov N. Novikova, Cand. of Sci. (Med.), Associate Professor of the Department of Pulmonology

6-8, L’va Tolstogo str., Saint Petersburg, 197022



References

1. Avdeev S. N., Aisanov Z. R., Belevsky A. S. et al. Idiopathic pulmonary fibrosis: federal clinical guidelines for diagnosis and treatment. Pulmonology. 2022;32(3):473–495. (In Russ.). https://doi.org/10.18093/08690189-2022-32-3-473-495.

2. Ilkovich M. M., Novikova L. N. Idiopathic interstitial pneumonia: a unifying concept. Doctor.Ru. 2018;148(4):14–17. (In Russ.).

3. Wells A. U., Flaherty K. R., Brown K. K. et al. Nintedanib in patients with progressive fibrosing interstitial lung diseases-subgroup analyses by interstitial lung disease diagnosis in the INBUILD trial: a randomised, double-blind, placebo-controlled, parallel-group trial. Lancet Respir Med. 2020;8(5):453–460. https://doi.org/10.1016/S22132600(20)30036-9. PMID: 32145830.

4. Wongkarnjana A., Scallan C., Kolb M. R. J. Progressive fibrosing interstitial lung disease: treatable traits and therapeutic strategies. Curr Opin Pulm Med. 2020;26(5):436–442. https://doi.org/10.1097/MCP.0000000000000712. PMID: 32657838.

5. Ilkovich M. M., Novikova L. N., Speranskaya A. A., Dvorakovskaya I. V. Progressive fibrosing pulmonary disease. Controversial aspects of the problem. Therapeutic archive. 2023;95(3):255–259. (In Russ.). https://doi.org/10.26442/00403660.2023.03.202075.

6. Putov N. V., Ilkovich M. M. Fibrosing alveolitis. L., Medicine, 1986. 168 p. (In Russ.).

7. Raghu G., Remy-Jardin M., Richeldi L. et al. Idiopathic Pulmonary Fibrosis (an Update) and Progressive Pulmonary Fibrosis in Adults: An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline. Am J Respir Crit Care Med. 2022;205(9):e18–e47. https://doi.org/10.1164/rccm.202202-0399ST. PMID: 35486072; PMCID: PMC9851481.


Review

For citations:


Ilkovich M.M., Novikova L.N. Progressive fibrosing pulmonary disease: from old misconceptions to a new understanding. New St. Petersburg Medical Records. 2025;(3):51-58. (In Russ.) https://doi.org/10.24884/1609-2201-2025-104-3-51-58

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ISSN 1609-2201 (Print)