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Safety analysis of statins

https://doi.org/10.24884/1609-2201-2026-105-2-11-18

Abstract

This article examines the efficacy and safety of statins. It examines the main reasons for failure to achieve target lipid levels. The causes of adverse reactions to these medications, their incidence, and possible mechanisms for the development of statin-associated muscle symptoms are analyzed. The article discusses drug interactions between statins and other medications, particularly the coadministration of statins and P2Y12 platelet receptor inhibitors, primarily ticagrelor.

About the Authors

O. D. Belyaeva
Pavlov University
Russian Federation

Olga D. Belyaeva, Dr. of Sci. (Med.), Professor, Professor of the Department of Faculty Therapy with a course in Endocrinology, Cardiology with the Clinic named after acad. G. F. Lang

Saint Petersburg



O. A. Berkovich
Pavlov University
Russian Federation

Olga A. Berkovich, Dr. of Sci. (Med.), Professor, Professor of the Department of Faculty Therapy with a course in Endocrinology, Cardiology with the Clinic named after acad. G. F. Lang 

6–8 L'va Tolstogo St., Saint Petersburg, 197022



O. N. Zhdanova
Pavlov University
Russian Federation

Olga N. Zhdanova, Cand. of Sci. (Med.), assistant professor, assistant professor of the Department of Faculty Therapy with a course in Endocrinology, Cardiology with the Clinic named after acad. G. F. Lang

Saint Petersburg



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Review

For citations:


Belyaeva O.D., Berkovich O.A., Zhdanova O.N. Safety analysis of statins. New St. Petersburg Medical Records. 2026;(2):11-18. (In Russ.) https://doi.org/10.24884/1609-2201-2026-105-2-11-18

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ISSN 1609-2201 (Print)