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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">spbmedicalrecords</journal-id><journal-title-group><journal-title xml:lang="ru">Новые Санкт-Петербургские врачебные ведомости</journal-title><trans-title-group xml:lang="en"><trans-title>New St. Petersburg Medical Records</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1609-2201</issn><publisher><publisher-name>Первый Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/1609-2201-2025-104-1-22-31</article-id><article-id custom-type="elpub" pub-id-type="custom">spbmedicalrecords-61</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LITERATURE REVIEWS</subject></subj-group></article-categories><title-group><article-title>Спондилоартриты и ВИЧ-инфекция, особенности течения и лечения</article-title><trans-title-group xml:lang="en"><trans-title>Spondyloarthritis and HIV infection, features of course and treatment</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0080-117X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шашко</surname><given-names>К. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Shashko</surname><given-names>K. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шашко Ксения Сергеевна, ординатор первого года</p><p>Санкт-Петербург, ул. Кирочная, д. 41</p></bio><bio xml:lang="en"><p>Ksenia S. Shashko, sixth year student of the Faculty of Medicine</p><p>41, Kirochnaya str., Saint Petersburg, 191015</p></bio><email xlink:type="simple">kseniya.shashko@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3500-7256</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гайдукова</surname><given-names>И. З.</given-names></name><name name-style="western" xml:lang="en"><surname>Gaydukova</surname><given-names>I. Z.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гайдукова Инна Зурабиевна, доктор медицинских наук, заместитель директора НИИ ревматологии, профессор кафедры терапии, ревматологии, экспертизы временной нетрудоспособности и качества медицинской помощи им. Э. Э. Эйхвальда</p><p>Санкт-Петербург, ул. Кирочная, д. 41</p></bio><bio xml:lang="en"><p>Inna Z. Gaydukova, Dr. of Sci. (Med.), Deputy Director of the Research Institute of Rheumatology, Professor of the Department of Therapy, Rheumatology, Examination of Temporary Disability and Quality of Medical Care named after. E.E. Eichwald</p><p>41, Kirochnaya str., Saint Petersburg, 191015</p></bio><email xlink:type="simple">ubp1976@list.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Северо-Западный государственный медицинский университет им. И. И. Мечникова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>North-Western State Medical University named after I. I. Mechnikov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Северо-Западный государственный медицинский университет им. И. И. Мечникова; Клиническая ревматологическая больница № 25 имени В. А. Насоновой</institution><country>Россия</country></aff><aff xml:lang="en"><institution>North-Western State Medical University named after I. I. Mechnikov; St. Petersburg Clinical Rheumatology Hospital No. 25 named after V. A. Nasonova</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>23</day><month>07</month><year>2025</year></pub-date><volume>0</volume><issue>1</issue><fpage>22</fpage><lpage>31</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шашко К.С., Гайдукова И.З., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Шашко К.С., Гайдукова И.З.</copyright-holder><copyright-holder xml:lang="en">Shashko K.S., Gaydukova I.Z.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.docved.ru/jour/article/view/61">https://www.docved.ru/jour/article/view/61</self-uri><abstract><p>ВИЧ-инфекция является распространенным заболеванием, часто сопряженным с другими патологиями, в частности ревматологического профиля, такими как спондилоартриты. Наличие ВИЧ-инфекции может изменять течение спондилоартритов и накладывает ограничения на их лечение ввиду иммуонсупрессивного характера последнего. Вместе с тем прогресс в лечении ВИЧ-инфекции и спондилоартритов привел к изменению природного течения указанного сочетания болезней и появлению новых перспективных подходов к лечению пациентов с ВИЧ и СпА. В представленной работе произведена систематизация международного опыта лечения данной когорты пациентов с учетом современных тенденций.</p></abstract><trans-abstract xml:lang="en"><p>HIV infection is a very common disease, often associated with other pathologies, in particular rheumatological ones, such as spondyloarthritis. The presence of HIV infection can change the course of spondyloarthritis, and imposes certain limitations on their treatment. At the same time, progress in the treatment of HIV infection and spondyloarthritis has led to a change in the natural course of this combination of diseases and the emergence of new promising approaches to the treatment of patients with HIV and SpA. The presented work systematizes international experience in treating this cohort of patients, taking into account current trends.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ВИЧ</kwd><kwd>СПИД</kwd><kwd>спондилоартрит</kwd><kwd>генно-инженерные биологические препараты</kwd><kwd>НПВП</kwd><kwd>глюкокортикоиды</kwd><kwd>ингибиторы ФНО-α</kwd><kwd>ингибиторы интерлейкина-17</kwd><kwd>ингибиторы интерлейкина-12/23</kwd><kwd>таргетные препараты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>HIV</kwd><kwd>AIDS</kwd><kwd>spondyloarthritis</kwd><kwd>TNF-α</kwd><kwd>comorbidity</kwd><kwd>treatment</kwd><kwd>biologics</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Клинические рекомендации. ВИЧ-инфекция у взрослых. 2020. 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