spbmedicalrecordsНовые Санкт-Петербургские врачебные ведомостиNew St. Petersburg Medical Records1609-2201Первый Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова10.24884/1609-2201-2024-103-3-81-89spbmedicalrecords-38Research ArticleОБЗОРЫ ЛИТЕРАТУРЫLITERATURE REVIEWSРоль эндотелиальной дисфункции и кишечной микробиоты в развитии метаболического синдромаRole of endothelial dysfunction and intestinal microbiota in the development metabolic syndromehttps://orcid.org/0000-0001-5111-2131ШишкинА. Н.ShishkinA. N.

Шишкин Александр Николаевич, доктор медицинских наук, профессор, заведующий кафедрой факультетской терапии

199034, Санкт-Петербург, Университетская наб., 7/9

Alexandr N. Shishkin, Dr. of Sci. (Med.), Professor, Head of the Department of Faculty Therapy

/9 Universitetskaya Emb., Saint Petersburg, 199034

alexshishkin@bk.ruСанкт-Петербургский государственный университетРоссияSaint-Petersburg State UniversityRussian Federation202428012025038189Copyright © Шишкин А.Н., 20252025Шишкин А.Н.Shishkin A.N.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.docved.ru/jour/article/view/38

В статье представлены данные о патогенезе возникновения дисфункции эндотелия при метаболическом синдроме. Описаны клинические и патогенетические особенности эндотелиальной дисфункции. Отдельные виды бактерий микробиоты кишечника могут рассматриваться как предикторы развития метаболического синдрома.

In the article the data is about the pathogenesis of endothelial dysfunction in metabolic syndrome. The clinical picture and pathogenic particularities are described. According to recent studies the role of gut microbiota in the development of metabolic syndrome is not in doubt. Specific bacteria species can be considered as predictors of the metabolic syndrome presence.

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The authors declare that there are no conflicts of interest present.