spbmedicalrecordsНовые Санкт-Петербургские врачебные ведомостиNew St. Petersburg Medical Records1609-2201Первый Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова10.24884/1609-2201-2025-104-3-19-29spbmedicalrecords-102Research ArticleОБЗОРЫ ЛИТЕРАТУРЫLITERATURE REVIEWSПеринатальные факторы риска хронической болезни почекPerinatal risk factors for chronic kidney diseasehttps://orcid.org/0000-0002-9455-1043РумянцевА. Ш.RumyantsevA. Sh.

Румянцев Александр Шаликович, доктор медицинских наук, профессор кафедры факультетской терапии медицинского факультета

199106, Санкт-Петербург, 21-я линия В. О., д. 8а

Alexander Sh. Rumyantsev, Dr. of Sci. (Med.), Professor of the Department of Faculty Therapy of the Medical Institute

21st line V. O., 8a, Saint Petersburg, 199106

rash.56@mail.ruhttps://orcid.org/0000-0002-5616-3488КучерА. Г.KucherA. G.

Кучер Анатолий Григорьевич, доктор медицинских наук, профессор, профессор кафедры пропедевтики внутренних болезней с клиникой им. акад. М. Д. Тушинского

Санкт-Петербург

Anatoliy G. Kucher, Dr. of Sci. (Med.), Professor, Professor of the Department of Propaedeutics of Internal Diseases with clinic named after acad. M. D. Tushinksy

Saint Petersburg

prof.kucher@yandex.ruСанкт-Петербургский государственный университет, Медицинский институтРоссияSaint Petersburg State UniversityRussian FederationПервый Санкт-Петербургский государственный медицинский университет имени академика И. П. ПавловаРоссияPavlov UniversityRussian Federation202511122025031929Copyright © Румянцев А.Ш., Кучер А.Г., 20252025Румянцев А.Ш., Кучер А.Г.Rumyantsev A.S., Kucher A.G.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.docved.ru/jour/article/view/102

Широкая распространенность хронической болезни почек (ХБП) обусловлена разнообразием модифицируемых и немодифицируемых факторов риска. Среди второй группы наиболее важными представляются такие факторы перинатального риска, как преждевременные роды, задержка внутриутробного развития, преэклампсия  и  низкая масса тела при рождении.

В статье в рамках гипотезы фетального программирования заболеваний взрослых обсуждаются распространенность этих осложнений и возможные механизмы формирования ХБП как у матери, так и у ребенка.

The widespread prevalence of chronic kidney disease (CKD) is due to a variety of modifiable and unmodifiable risk factors. Among the second group, such perinatal risk factors as premature birth, delayed intrauterine development, preeclampsia, and low birth weight are considered the most important.

Within the framework of the hypothesis of fetal programming of adult diseases, the article discusses the prevalence of these complications and possible mechanisms of CKD formation in both mother and child.

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The authors declare that there are no conflicts of interest present.